When infected, the Skene's gland will become enlarged and tender.
A simple incision and drainage of the gland will generally result in complete resolution. Topical anesthetic (20% benzocaine, or "Hurricaine") can be applied to the cyst with a cotton-tipped applicator and allowed to sit for 3-4 minutes. A single stab wound by a scalpel opens the abscess and allows for drainage of the pus.
Cultures, particularly for gonorrhea, should be obtained.
Good choices for antibiotics would include those most helpful for treating urethritis:
OB-GYN 101: Introductory
Obstetrics & Gynecology
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